வேர்ல்ட் ஜர்னல் ஆஃப் பார்மகாலஜி & டாக்ஸிகாலஜி

சுருக்கம்

The New Plant Growth Regulators Based On Derivatives Of Oxazole And Oxazolopyrimidine

ScD Victoria Anatolyivna Tsygankova

In our work to study cytokinin-like activity of chemical low molecular weight heterocyclic compounds, derivatives of
oxazolopyrimidine and oxazole we used the specific bioassay conducted on the cotyledons isolated from seeds of
muscat pumpkin (Cucurbita moschata Duch. et Poir.) cultivar Gilea. The activity of derivatives of oxazolopyrimidine
and oxazole was compared with the activity of plant hormone cytokinin Kinetin. The specific bioassay on cytokinin-
like activity showed that among derivatives of oxazolopyrimidine and oxazole, used at the concentration 10-9M
in water solution, the highest activity on the growth of biomass of cotyledons isolated from seed of muscat pumpkin
demonstrated the compounds: the compound №2 - 2,5-diphenyl[1,3]oxazolo[5,4-d]pyrimidin-7(6H)-one, which contains
phenyl substituent at the 5th position of pyrimidine fragment, the compound №4 - 7-aminо-5-(4-ethylphenyl)-2-
phenyl[1,3]oxazolo[5,4-d]pyrimidine, which contains amino group at the 7th position of pyrimidine fragment, and the
compound №6 - 2-tolyl-5-(piperidin-1-ylsulfonyl)-1,3-oxazole-4-carbonitrile, which contains tolyl substituent at the
2nd position of oxazole. It is obvious that cytokinin-like activity on the growth of the biomass of cotyledons isolated
from seed of muscat pumpkin of derivatives of oxazolopyrimidine may depend on substituents at the 5th and 7th positions
of pyrimidine fragment, while as activity of compounds, derivatives of oxazole may depend on substituents at
the 2th position of oxazole. The obtained results confirmed the cytokinin-like effect of derivatives of oxazolopyrimidine
and oxazole on plant cell elongation, division, and differentiation that are the basic processes of plant growth. The
practical application of derivatives of oxazolopyrimidine and oxazole as new plant growth regulators was proposed.