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Platelet Rich Fibrin and Its Role in Regenerative Dentistry: A Mini Review

Ved V, Bhagat J, Gala V, Gabriela Fernandes

Platelets play a prime role in the field of regenerative dentistry. Platelet rich fibrin (PRF) comprises of a fibrin matrix consisting of platelet cytokines and an inventory of growth factors. These growth factors consist of proteins which are known to be involved with the cells during the process of tissue regeneration and growth. PRF application has surpassed other platelet concentrates like PRP due to its effortlessness and economical method of preparation, and also its prevention from the need of supplemental exogenous compounds like bovine thrombin and calcium chloride. This review attempts to contour the relevant composition regarding the technique of using platelet rich fibrin (PRF), various types of stem cell sources that have been identified, focusing on its preparation, advantages, and disadvantages of using it in dentistry.