அழற்சி, புற்றுநோய் மற்றும் ஒருங்கிணைந்த சிகிச்சைக்கான சர்வதேச இதழ்

சுருக்கம்

Human Leukocyte Antigen G as a Novel Target for Switch-based Chimeric Antigen Receptor Natural Killer Cell Therapy of Solid Cancer

peter D Canoll

Challenges present with chimeric antigen receptors (CARs) adoptive cell therapy against solid tumors have been lacking a ubiquitous tumor-associated antigen across different tumor types, tumor antigen expression heterogeneity, and the immunosuppressive nonphysical tumor microenvironment.  Thus, we developed a switch anti human leukocyte antigen (HLA)-G CAR that binds to HLA-G1~G7